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1

Substitution of Glu122 by Glutamine Revealed the Function of the Second Water Molecule as a Proton Donor in the Binuclear Metal Enzyme Creatininase

Kinuyo Yamashita, Yoshitaka Nakajima, Hayato Matsushita, Yoshiaki Nishiya, Ryuji Yamazawa, Yu-fan Wu, Futoshi Matsubara, Hiroshi Oyama, Kiyoshi Ito, Tadashi Yoshimoto

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 3.47 MB

english, 2010

2

Distinct expressions of microRNAs that directly target estrogen receptor α in human breast cancer

Nobuyasu Yoshimoto, Tatsuya Toyama, Satoru Takahashi, Hiroshi Sugiura, Yumi Endo, Mai Iwasa, Yoshitaka Fujii, Hiroko Yamashita

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 1.63 MB

english, 2011

3

Quantum Dipole Effects in a Silicon Transistor under High Electric Fields

Saito, Shinichi, Li, Zuo, Yoshimoto, Hiroyuki, Tomita, Isao, Tsuchiya, Yoshishige, Sasago, Yoshitaka, Arimoto, Hideo, Liu, Fayong, Husain, Muhammad Khaled, Hisamoto, Digh, Rutt, Harvey N., Kurihara, S

Journal:

Journal of the Physical Society of Japan

Year:

2018

Language:

english

File:

PDF, 21.50 MB

english, 2018

4

Fabrication of ferromagnetic Ni epitaxial thin film by way of hydrogen reduction of NiO

Akifumi Matsuda, Shusaku Akiba, Masayasu Kasahara, Takahiro Watanabe, Yasuyuki Akita, Yoshitaka Kitamoto, Takeo Tojo, Hitoshi Kawaji, Tooru Atake, Kouji Koyama, Mamoru Yoshimoto

Journal:

Thin Solid Films

Year:

2008

Language:

english

File:

PDF, 320 KB

english, 2008

5

Mutations in intron 3 of GH-1 gene associated with isolated GH deficiency type II in three Japanese families

Takashi Kamijo, Yoshitaka Hayashi, Akira Shimatsu, Eiichi Kinoshita, Masaaki Yoshimoto, Masamichi Ogawa, Hisao Seo

Journal:

Clinical Endocrinology

Year:

1999

Language:

english

File:

PDF, 190 KB

english, 1999

6

Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages

Toshiki Sakashita, Yoshitaka Takahashi, Takahiro Kinoshita, Tanihiro Yoshimoto

Journal:

Year:

1999

Language:

english

File:

PDF, 726 KB

english, 1999

7

High estrogen receptor expression and low Ki67 expression are associated with improved time to progression during first-line endocrine therapy with aromatase inhibitors in breast cancer

Yumi Endo, Tatsuya Toyama, Satoru Takahashi, Hiroshi Sugiura, Nobuyasu Yoshimoto, Mai Iwasa, Shunzo Kobayashi, Yoshitaka Fujii, Hiroko Yamashita

Journal:

International Journal of Clinical Oncology

Year:

2011

Language:

english

File:

PDF, 1.58 MB

english, 2011

8

Predictors of response to exemestane as primary endocrine therapy in estrogen receptor–positive breast cancer

Hiroko Yamashita, Satoru Takahashi, Yukashi Ito, Toshinari Yamashita, Yoshiaki Ando, Tatsuya Toyama, Hiroshi Sugiura, Nobuyasu Yoshimoto, Shunzo Kobayashi, Yoshitaka Fujii, Hirotaka Iwase

Journal:

Year:

2009

Language:

english

File:

PDF, 324 KB

english, 2009

9

Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women

Nobuyasu Yoshimoto, Takeshi Nishiyama, Tatsuya Toyama, Satoru Takahashi, Norio Shiraki, Hiroshi Sugiura, Yumi Endo, Mai Iwasa, Yoshitaka Fujii, Hiroko Yamashita

Journal:

Year:

2011

Language:

english

File:

PDF, 171 KB

english, 2011

10

An anti-platelet agent, OPC-29030, inhibits translocation of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid production in human platelets

Yasushi Ozeki, Yoshie Nagamura, Hideki Ito, Fumiko Unemi, Yukio Kimura, Takehiro Igawa, Jun-ichi Kambayashi, Yoshitaka Takahashi, Tanihiro Yoshimoto

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 182 KB

english, 1999

11

In vivo analysis of mammary and non-mammary tumorigenesis in MMTV-cyclin D1 transgenic mice deficient in p53

Yoshitaka Hosokawa, Alexandros Papanikolaou, Robert D. Cardiff, Katsuhiko Yoshimoto, Megan Bernstein, Timothy C. Wang, Emmett V. Schmidt, Andrew Arnold

Journal:

Transgenic Research

Year:

2001

Language:

english

File:

PDF, 101 KB

english, 2001

12

Evidence for Direct Association of Vpr and Matrix Protein p17 within the HIV-1 Virion

AKIHIKO SATO, JUN YOSHIMOTO, YOSHITAKA ISAKA, SHIGERU MIKI, AKEMI SUYAMA, AKIO ADACHI, MASANORI HAYAMI, TAMIO FUJIWARA, OSAMU YOSHIE

Journal:

Year:

1996

Language:

english

File:

PDF, 157 KB

english, 1996

13

Autophagy in plants and phytopathogens

Kohki Yoshimoto, Yoshitaka Takano, Yasuyoshi Sakai

Journal:

Year:

2010

Language:

english

File:

PDF, 363 KB

english, 2010

14

Continuous antibody production by phytohemagglutinin-L-aggregated hybridoma cells

Hiroyuki Takamatsu, Hiroo Kawajiri, Yoshitaka Takahashi, Abdul Manaf Ali, Tanihiro Yoshimoto

Journal:

Journal of Immunological Methods

Year:

1999

Language:

english

File:

PDF, 166 KB

english, 1999

15

Arachidonate 12-lipoxygenases

Tanihiro Yoshimoto, Yoshitaka Takahashi

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

16

Growth stimulation and epidermal growth factor receptor induction in cyclooxygenase-overexpressing human colon carcinoma cells

Tanihiro Yoshimoto, Takahiro Kinoshita, Yoshitaka Takahashi, Toshiki Sakashita, Hiroyasu Inoue, Tadashi Tanabe

Journal:

Prostaglandins and Other Lipid Mediators

Year:

1999

Language:

english

File:

PDF, 68 KB

english, 1999

17

Characterization of arachidonate 8-lipoxygenase expressed in COS-7 and Escherichia coli

Na Qiao, Yoshitaka Takahashi, Hiroyuki Takamatsu, Tanihiro Yoshimoto

Journal:

Prostaglandins and Other Lipid Mediators

Year:

1999

Language:

english

File:

PDF, 74 KB

english, 1999

18

Cyclooxygenase 2 and prostaglandin E2 regulate the attachment of calcium oxalate crystals to renal epithelial cells

Katsuhito Miyazawa, Yoshitaka Takahashi, Nobuyo Morita, Manabu T Moriyama, Takeo Kosaka, Matomo Nishio, Tanihiro Yoshimoto, Koji Suzuki

Journal:

International Journal of Urology

Year:

2012

Language:

english

File:

PDF, 533 KB

english, 2012

19

Cyclooxygenase-2 Stimulates Production of Amyloid β-Peptide in Neuroblastoma × Glioma Hybrid NG108-15 Cells

Keiichi Kadoyama, Yoshitaka Takahashi, Haruhiro Higashida, Tadashi Tanabe, Tanihiro Yoshimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 271 KB

english, 2001

20

2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis

Yoshimoto Tanihiro, Yokoyama Chieko, Ochi Kenkichi, Yamamoto Shozo, Maki Yoshitaka, Ashida Yasuko, Terao Shinji, Shiraishi Mitsuru

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1982

Language:

english

File:

PDF, 401 KB

english, 1982

21

Induction of cyclooxygenase and suppression of 12-lipoxygenase in human erythroleukemia cells upon phorbol ester-induced differentiation

Ishtiaq Mahmud, Toshiko Suzuki, Yasuchika Yamamoto, Hiroshi Suzuki, Yoshitaka Takahashi, Tanihiro Yoshimoto, Shozo Yamamoto

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1993

Language:

english

File:

PDF, 707 KB

english, 1993

22

Immunoaffinity purification and cDNA cloning of human platelet prostaglandin endoperoxide synthase (cyclooxygenase)

Yoshitaka Takahashi, Natsuo Ueda, Tanihiro Yoshimoto, Shozo Yamamoto, Chieko Yokoyama, Atsuro Miyata, Tadashi Tanabe, Ichiro Fuse, Akira Hattori, Akira Shibata

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 453 KB

english, 1992

23

Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase

Yoshitaka Takahashi, Hong Zhu, Wanpeng Xu, Takashi Murakami, Tadao Iwasaki, Hiroaki Hattori, Tanihiro Yoshimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 224 KB

english, 2005

24

Synthesis of 8,9-leukotriene A4 by murine 8-lipoxygenase

Hiroo Kawajiri, Yingshi Piao, Yoshitaka Takahashi, Takashi Murakami, Nobuyuki Hamanaka, Tanihiro Yoshimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

25

Low-dose GH supplementation reduces the TLR2 and TNF-α expressions in visceral fat

Yoshitaka Kubota, Hiroyuki Unoki, Hideaki Bujo, Naoaki Rikihisa, Akikazu Udagawa, Shinya Yoshimoto, Masaharu Ichinose, Yasushi Saito

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 358 KB

english, 2008

26

Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion

Mayumi Okawa, Kenji Fujii, Katsuya Ohbuchi, Mayumi Okumoto, Katsumi Aragane, Hiromu Sato, Yoshitaka Tamai, Toru Seo, Yoshiki Itoh, Ryo Yoshimoto

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

27

Locally administered T cells from mice immunized with lipopolysaccharide (LPS) accelerate LPS-induced bone resorption

Yukio Ozaki, Takashi Ukai, Masayuki Yamaguchi, Miho Yokoyama, Esperanza R. Ayón Haro, Mayumi Yoshimoto, Takashi Kaneko, Miho Yoshinaga, Hirotaka Nakamura, Chiaki Shiraishi, Yoshitaka Hara

Journal:

Year:

2009

Language:

english

File:

PDF, 1.75 MB

english, 2009

28

Crystal Structures of Creatininase Reveal the Substrate Binding Site and Provide an Insight into the Catalytic Mechanism

Tadashi Yoshimoto, Nobutada Tanaka, Naota Kanada, Takahiko Inoue, Yoshitaka Nakajima, Mamoru Haratake, Kazuo T Nakamura, Yue Xu, Kiyoshi Ito

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 5.47 MB

english, 2004

29

d-3-Hydroxybutyrate Dehydrogenase from Pseudomonas fragi: Molecular Cloning of the Enzyme Gene and Crystal Structure of the Enzyme

Kiyoshi Ito, Yoshitaka Nakajima, Emi Ichihara, Kyohei Ogawa, Naoko Katayama, Kanako Nakashima, Tadashi Yoshimoto

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 669 KB

english, 2006

30

Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis

Kiyoshi Ito, Yoshitaka Nakajima, Yue Xu, Nozomi Yamada, Yuko Onohara, Takashi Ito, Futoshi Matsubara, Tsutomu Kabashima, Koji Nakayama, Tadashi Yoshimoto

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.02 MB

english, 2006

31

Novel Inhibitor for Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis and Details of Substrate-recognition Mechanism

Yue Xu, Yoshitaka Nakajima, Kiyoshi Ito, Heng Zheng, Hiroshi Oyama, Ulrich Heiser, Torsten Hoffmann, Ulf-Torsten Gärtner, Hans-Ulrich Demuth, Tadashi Yoshimoto

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 2.19 MB

english, 2008

32

Does hypofrontality expand to global brain area in progression of schizophrenia?: A cross-sectional study between first-episode and chronic schizophrenia

Nobuhisa Kanahara, Eiji Shimizu, Yoshimoto Sekine, Yoshitaka Uchida, Takayuki Shibuya, Hiroshi Yamanaka, Tasuku Hashimoto, Takuya Asaka, Tsuyoshi Sasaki, Ryosuke Miyatake, Toshihiko Ohkami, Goro Fukam

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2009

Language:

english

File:

PDF, 607 KB

english, 2009

33

Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2

Yoshitaka Takahashi, Futoshi Kawahara, Masakuni Noguchi, Koichi Miwa, Hiroshi Sato, Motoharu Seiki, Hiroyasu Inoue, Tadashi Tanabe, Tanihiro Yoshimoto

Journal:

Year:

1999

Language:

english

File:

PDF, 210 KB

english, 1999

34

Gonadotropin-releasing hormone neurons in the gourami midbrain: a double labeling study by immunocytochemistry and tracer injection

Naoyuki Yamamoto, Yoshitaka Oka, Masami Yoshimoto, Nobuhiko Sawai, James S Albert, Hironobu Ito

Journal:

Neuroscience Letters

Year:

1998

Language:

english

File:

PDF, 370 KB

english, 1998

35

Molecular mechanism of low density lipoprotein oxidation by 12-lipoxygenase-overexpressing macrophages

Tanihiro Yoshimoto, Yoshitaka Takahashi, Wanpeng Xu, Takahiro Kinoshita, Toshiki Sakashita, Hiroshi Mabuchi

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 248 KB

english, 2002

36

12-Lipoxygenase increases neuronal excitability by inhibiting M-type potassium channels

Yoshitaka Takahashi, Tanihiro Yoshimoto, Naoto Hoshi, Haruhiro Higashida

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 69 KB

english, 2002

37

Overexpression of cyclooxygenase-2 stimulates amyloid β-peptide production in neuronal cells

Keiichi Kadoyama, Yoshitaka Takahashi, Haruhiro Higashida, Tadashi Tanabe, Tanihiro Yoshimoto

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

38

Growth stimulation and induction of epidermal growth factor receptor by overexpression of cyclooxygenases 1 and 2 in human colon carcinoma cells

Takahiro Kinoshita, Yoshitaka Takahashi, Toshiki Sakashita, Hiroyasu Inoue, Tadashi Tanabe, Tanihiro Yoshimoto

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

1999

Language:

english

File:

PDF, 411 KB

english, 1999

39

Leukotriene A synthase activity of purified mouse skin arachidonate 8-lipoxygenase expressed in Escherichia coli

Na Qiao, Yoshitaka Takahashi, Hiroyuki Takamatsu, Tanihiro Yoshimoto

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

1999

Language:

english

File:

PDF, 235 KB

english, 1999

40

[AIP POWDERS AND GRAINS 2009: PROCEEDINGS OF THE 6TH INTERNATIONAL CONFERENCE ON MICROMECHANICS OF GRANULAR MEDIA - Golden (Colorado) (13–17 July 2009)] AIP Conference Proceedings - Material Characteristics of Clinker Ash and Examination of Applicability for Embankment

Wakatsuki, Yoshitaka, Hyodo, Masayuki, Yoshimoto, Norimasa, Nakashita, Akifumi, Ikeda, Takashi, Nakagawa, Masami, Luding, Stefan

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

41

12-Lipoxygenase overexpression in rodent NG108-15 cells enhances membrane excitability by inhibiting M-type K+ channels

Yoshitaka Takahashi, Hiroo Kawajiri, Tanihiro Yoshimoto, Naoto Hoshi, Haruhiro Higashida

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 312 KB

english, 1999

42

2407 Localization of midbrain gnrh neurons: A double labeling study by immunohistochemistry and tracer injection to the spinal cord

Naoyuki Yamamoto, Yoshitaka Oka, Masami Yoshimoto, Hironobu Ito

Journal:

Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 100 KB

english, 1996

43

Orbitofrontal cortex abnormality and deficit schizophrenia

Kanahara, Nobuhisa, Sekine, Yoshimoto, Haraguchi, Tadashi, Uchida, Yoshitaka, Hashimoto, Kenji, Shimizu, Eiji, Iyo, Masaomi

Journal:

Schizophrenia Research

Year:

2013

Language:

english

File:

PDF, 681 KB

english, 2013

44

FOXA1 expression after neoadjuvant chemotherapy is a prognostic marker in estrogen receptor-positive breast cancer

Kawase, Mai, Toyama, Tatsuya, Takahashi, Satoru, Sato, Shinya, Yoshimoto, Nobuyasu, Endo, Yumi, Asano, Tomoko, Kobayashi, Shunzo, Fujii, Yoshitaka, Yamashita, Hiroko

Journal:

Year:

2015

Language:

english

File:

PDF, 690 KB

english, 2015

45

Neonatal onset of medium-chain Acyl-CoA dehydrogenase deficiency in two siblings

Nobukuni, Yoshitaka, Yokoo, Tetsuya, Ohtani, Yoshinobu, Endo, Fumio, Aoki, Shigeru, Yoshinaga, Muneyoshi, Matsumoto, Takashi, Yoshimoto, Masaaki, Tsuji, Yoshiro, Matsuda, Ichiro

Journal:

Brain and Development

Year:

1988

Language:

english

File:

PDF, 2.18 MB

english, 1988

46

Determination of Antihypertensive Peptides from an Izumi Shrimp Hydrolysate

NII, Yoshitaka, FUKUTA, Kazuhiro, YOSHIMOTO, Ryoko, SAKAI, Kentaro, OGAWA, Tadashi

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2008

Language:

english

File:

PDF, 87 KB

english, 2008

47

Phase transition-induced rapid permeabilization of liposome membranes composed of milk-sphingomyelin

Yoshimoto, Makoto, Todaka, Yoshitaka

Journal:

European Journal of Lipid Science and Technology

Year:

2014

Language:

english

File:

PDF, 232 KB

english, 2014

48

Self-formed silicon quantum wires on ultrasmooth sapphire substrates

Yanagiya, Shun-ichi, Kamimura, Shunsuke, Fujii, Masanori, Ishida, Makoto, Moriyasu, Yoshitaka, Matsui, Masahiro, Yoshimoto, Mamoru, Ohnishi, Tsuyoshi, Yoshida, Kenji, Sasaki, Kenji, Koinuma, Hideomi

Journal:

Applied Physics Letters

Year:

1997

Language:

english

File:

PDF, 295 KB

english, 1997

49

Essential Roles of Lipoxygenases in LDL Oxidation and Development of Atherosclerosis

Takahashi, Yoshitaka, Zhu, Hong, Yoshimoto, Tanihiro

Journal:

Antioxidants & Redox Signaling

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

50

Immunohistochemical determination of the miR-1290 targetarylamine N-acetyltransferase 1 (NAT1)as a prognostic biomarker in breast cancer

Endo, Yumi, Yamashita, Hiroko, Takahashi, Satoru, Sato, Shinya, Yoshimoto, Nobuyasu, Asano, Tomoko, Hato, Yukari, Dong, Yu, Fujii, Yoshitaka, Toyama, Tatsuya

Journal:

Year:

2014

Language:

english

File:

PDF, 597 KB

english, 2014

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